Regulation of cytochrome P450 3A4 by small vault RNAb derived from the non-coding vault RNA1 of multidrug resistance-linked vault particle
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چکیده
منابع مشابه
The Telomerase/Vault-Associated Protein Tep1 Is Required for Vault RNA Stability and Its Association with the Vault Particle
Vaults and telomerase are ribonucleoprotein (RNP) particles that share a common protein subunit, TEP1. Although its role in either complex has not yet been defined, TEP1 has been shown to interact with the mouse telomerase RNA and with several of the human vault RNAs in a yeast three-hybrid assay. An mTep1(-/-) mouse was previously generated which resulted in no apparent change in telomere leng...
متن کاملsolitary plasmocytoma of the vault
solitary plasmocytoma is rarely located in the cranial vault. we report one case of solitary plasmacytoma of the skull and discuss the clinical features and treatment of this uncommon tumor in the light of the published cases. a 46-year-old moroccan male, without previous history consulted for a swelling in medial frontal and paramedian region. on clinical examination the clinical examination r...
متن کاملEvolution of vault RNAs.
Vault RNAs (vtRNAs) are small, about 100 nt long, polymerase III transcripts contained in the vault particles of eukaryotic cells. Presumably due to their enigmatic function, they have received little attention compared with most other noncoding RNA (ncRNA) families. Their poor sequence conservation makes homology search a complex and tedious task even within vertebrates. Here we report on a sy...
متن کاملManagement of vault prolapse
Definition Vaginal vault prolapse is defined as descent of the vaginal cuff below a point that is 2 cm less than the total vaginal length above the plane of the hymen. Or simply, the uppermost part of the vagina descends from its normal position, sometimes out through the vaginal opening. Uterovaginal prolapse has been described as an entity as early as 1550 BC in ancient Egyptian literature an...
متن کاملPlasmocytoma of the skull vault.
AIM Plasma cell tumours include solitary plasmocytoma, multiple plasmocytoma and multiple myeloma. Herein we report a case of plasmocytoma of the skull. CASE HISTORY A 49 year-old-man suffered from amnesia, irritability and a rubbery swelling which was gradually increased approximately to 4-5 cm in diameter at the frontal vertex over a year. His neurological examination was normal. The skull ...
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2016
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2016.5228